Peptide appearance
Lyophilized form helps protect peptide quality. Peptides are supplied as a dry powder, which may look like a compact "puck" or a lighter powder inside the vial.
Because the peptide is dry, it does not require refrigerated shipping during normal transit, including warm seasonal conditions. For longer storage, follow the storage guidance in the product description.
Appearance can vary. The stated peptide content is checked through third-party analysis.
Read more in the product description.
Solution not bundled
Peptides are delivered as lyophilized powder. This dry form helps preserve peptide quality during storage and transport and does not require refrigerated shipping during normal transit.
To prepare a solution, use a solvent such as Bacteriostatic water. It is sold separately, so add it only when you need it for peptide preparation.
Read more in the product description.
Metabolic small molecule
5-amino-1MQ
In stock
A quinolinium NNMT-inhibitor reference used in methylation and metabolism studies.
Order within — · ships Wed, 23 Sep Cutoff 10:00 · local time
Arrives Sep 28 - Sep 30 to Europe
More at checkout
5-amino-1MQ
Price range: 43,90 € through 104,50 €
NNMT-focused small-molecule reference for metabolism and NAD-adjacent pathway studies.
Research overview
5-amino-1MQ
5-amino-1MQ is shorthand for 5-amino-1-methylquinolinium, a small-molecule research compound rather than a peptide.
Laboratory work examines nicotinamide N-methyltransferase inhibition, methylation chemistry, and NAD-adjacent metabolism. The listed sources are a research starting point rather than a substitute for product evidence: the supplied material's exact form, lot, and measured characteristics must be established through its signed analytical record.
Compound information
Specifications
Molecular profile
- Molecular mass
- 286.11 g/mol
- CAS number
- 42464-96-0
- Molecular formula
- C10H11IN2
Material record
- Physical appearance
- Yellow to brown powder or lyophilized solid
- Salt form
- Iodide salt
- Solubility
- Soluble in DMSO and suitable polar laboratory solvents.
- Product note
- Small-molecule NNMT inhibitor reference compound; studied in nicotinamide metabolism, methylation pathway, and cellular metabolism assays; supplied strictly for research use only.
Laboratory care
Handling
Product storage
Sealed dry material: store at -20 °C, desiccated and protected from light. Prepared solutions require a solvent-specific validated stability protocol.
Material in transport
Keep the sealed container dry, protected from direct light, and within the product-specific laboratory transport conditions.
Storage of dry material
Keep the sealed reference material protected from moisture and light and follow the product-specific storage record maintained by Adria Science.
Storage of prepared laboratory solutions
Prepared laboratory solutions require compatible solvent selection, clean handling, and a documented laboratory stability policy.
Analytical documentation
Tests
Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 10mg
> 99.8%Purity by HPLC
Recorded QC panel
- AssayPeptide Screening 0.1% TFA
- 12.40 mg (± 0.06 mg)
- PurityPeptide Screening 0.1% TFA
- > 99.8%
- Identity (FTIR)Peptide Screening 0.1% TFA
- 996 (± 5)
- Identity (RT)Retention time
- 0.998 (± 0.005)
- Bacterial endotoxinUSP 85 / Eur. Ph. 2.6.14
- 0.286 EU/mg
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
Documentation is available on request
Contact us for the current record for this strength. We never substitute a generic or mismatched certificate.
Your batch is confirmed when your order is allocated.Source record
References
National Center for Biotechnology Information
PubChem Compound Summary: 5-Amino-1-methylquinolinium
Authoritative identity record for 5-amino-1MQ.
PubChem · View source ↗National Center for Biotechnology Information
NCBI Gene: NNMT nicotinamide N-methyltransferase
Authoritative gene record for the NNMT research target.
NCBI Gene · View source ↗Kraus D, Yang Q, Kong D, et al. · 2014
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
Primary NNMT-pathway study relevant to the compound's research target.
Nature · 10.1038/nature13198 View source ↗Neelakantan H, Wang HY, Vance V, Hommel JD, McHardy SF, Watowich SJ · 2017
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
Journal of medicinal chemistry · View source ↗Neelakantan H, Vance V, Wetzel MD, Wang HL, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ · 2018
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Biochemical pharmacology · View source ↗Neelakantan H, Brightwell CR, Graber TG, Maroto R, Wang HL, McHardy SF, Papaconstantinou J, Fry CS, Watowich SJ · 2019
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
Biochemical pharmacology · View source ↗Sampson CM, Dimet AL, Neelakantan H, Ogunseye KO, Stevenson HL, Hommel JD, Watowich SJ · 2021
Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
Scientific reports · View source ↗Awosemo O, Neelakantan H, Watowich S, Ma J, Wu L, Chow DS, Liang D · 2021
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
Journal of pharmaceutical and biomedical analysis · View source ↗Akar S, Duran T, Azzawri AA, Koçak N, Çelik Ç, Yıldırım Hİ · 2021
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · View source ↗Dimet-Wiley A, Wu Q, Wiley JT, Eswar A, Neelakantan H, Savidge T, Watowich S · 2022
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Scientific reports · View source ↗Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H · 2024
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
Diabetes, obesity & metabolism · View source ↗Customer reviews
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