Peptide appearance Lyophilized form

Metabolic Research

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GLP-1 (SM)

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A GLP-1 receptor research peptide used in controlled signalling and stability studies.

Available strengths
77,00 €
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GLP-1 (SM)

Price range: 77,00 € through 99,00 €

Long-acting GLP-1 analogue for incretin receptor and metabolic pathway studies.

SKU: ADRIA-SEMAGLUTIDE Categories: , Tags: ,

Research overview

GLP-1 (SM)

GLP-1 (SM), described in scientific literature as semaglutide, is a modified analogue of human GLP-1. Its molecular design includes an alpha-aminoisobutyric-acid substitution that limits DPP-4 degradation and a C18 fatty-diacid side chain linked through a spacer to support reversible albumin binding.

These structural changes are studied for their effects on molecular stability, circulation profile, and selective GLP-1-receptor signalling. The overview here describes the compound's identity and published research context; batch-specific analytical results remain in the signed certificate for the selected strength.

Compound information

Specifications

Molecular profile

Sequence
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEA-AEEA-gamma-Glu-C18 diacid)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly
Molecular mass
4113.58 g/mol
CAS number
910463-68-2
Molecular formula
C187H291N45O59

Material record

Physical appearance
White to off-white lyophilized powder
Solubility
Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
Product note
GLP-1 receptor pathway research compound; supplied strictly for research use only.

Laboratory care

Handling

Peptides in transport

Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.

Storage of lyophilized peptides

Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Up to 3 months
  • Refrigerated (2–8 °C): Up to 6 months
  • Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)

Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.

Storage of reconstituted peptides

Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.

The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Avoid prolonged storage
  • Refrigerated (2–8 °C): Typically 4–8 weeks
  • Frozen (-20 °C or below): Up to 3–4 months

To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.

Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.

Analytical documentation

Tests

On request

Documentation is available on request

Contact us for the current record for this strength. We never substitute a generic or mismatched certificate.

Your batch is confirmed when your order is allocated.
See all test results

Signed certificate

Source record

References

Lau J, Bloch P, Schäffer L, et al. · 2015

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

Molecular design and discovery history of semaglutide.

Journal of Medicinal Chemistry · 10.1021/acs.jmedchem.5b00726 View source ↗

National Center for Biotechnology Information

PubChem Compound Summary: Semaglutide

Authoritative identity record for semaglutide.

PubChem View source ↗

Wilding JPH, Batterham RL, Calanna S, et al. · 2021

Once-Weekly Semaglutide in Adults with Overweight or Obesity

Primary clinical research report for the compound described as semaglutide.

The New England Journal of Medicine · 10.1056/nejmoa2032183 View source ↗

National Center for Biotechnology Information

PubChem compound record

PubChem View source ↗

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