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Peptide appearance Lyophilized form

Neuroregulatory peptide

Selank

In stock

Selank is a synthetic peptide based on tuftsin and made of seven amino acids. Published studies look at GABA-related gene activity, cytokines, learning, memory, and pain-perception models.

Available strengths
33,00 
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Selank

Price range: 21,90 € through 33,00 €

Tuftsin-derived heptapeptide for neuropeptide and stress-pathway studies.

SKU: ADRIA-SELANK Category:

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Research overview

Selank

Selank has the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Its short sequence supports controlled identity, stability, and signalling studies.

Studies cover GABA-system markers, immune-cell signals, thinking tasks, and pain-response models. Each report applies only to its experimental conditions.

GABA and immune signalling

Studies measure GABA-system gene activity, cytokine markers, and links between nerve and immune signals. These are molecular and cellular research endpoints.

Each paper should be read with its exact tissue, model, and timing.

Cognitive and sensory models

Other studies use learning, memory, brain-injury, and pain-perception models. These endpoints need the original protocol and comparison group for context.

Compound information

Specifications

Molecular profile

Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular mass
751.9 g/mol
CAS number
129954-34-3
Molecular formula
C33H57N11O9

Material record

Physical appearance
White to off-white lyophilized powder
Solubility
Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
Product note
Tuftsin-derived heptapeptide analogue; supplied strictly for research use only.

Laboratory care

Handling

Peptides in transport

Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.

Storage of lyophilized peptides

Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Up to 3 months
  • Refrigerated (2–8 °C): Up to 6 months
  • Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)

Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.

Storage of reconstituted peptides

Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.

The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Avoid prolonged storage
  • Refrigerated (2–8 °C): Typically 4–8 weeks
  • Frozen (-20 °C or below): Up to 3–4 months

To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.

Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.

Analytical documentation

Latest test results

Latest published result

Liquilabs s.r.o.Signed Certificate of Analysis · 10mg

> 99.8%Purity by HPLC

Batch number
2025282
Tested
2026-05-28

Recorded QC panel

AssayPeptide screening
12.13 mg
PurityPeptide screening
> 99.8%
Identity (FTIR)FTIR spectrum
998
Identity (RT)Retention time
0.984

These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.

See all test results

Signed certificate

Source record

References

National Center for Biotechnology Information

PubChem Compound Summary: Selank

Authoritative identity record for Selank.

PubChem · View source ↗

Panikratova YR, Lebedeva IS, Sokolov OY, et al. · 2020

Functional Connectomic Approach to Studying Selank and Semax Effects

Experimental comparison of Selank and Semax in a functional-connectomics model.

Doklady Biological Sciences · 10.1134/s001249662001007x View source ↗

Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA, et al. · 2021

The Influence of Selank on the Level of Cytokines Under the Conditions of Social Stress

Experimental report on Selank in a cytokine-measurement model.

Current Reviews in Clinical and Experimental Pharmacology · 10.2174/1574884715666200704152810 View source ↗

Chemical Abstracts Service

CAS Common Chemistry: 129954-34-3

Authoritative CAS Registry Number record for Selank.

CAS Common Chemistry · View source ↗

National Center for Biotechnology Information

PubChem compound record

PubChem · View source ↗

Zozulia AA, Neznamov GG, Siuniakov TS, Kost NV, Gabaeva MV, Sokolov OIu, Serebriakova EV, Siranchieva OA, Andriushenko AV, Telesheva ES, Siuniakov SA, Smulevich AB, Miasoedov NF, Seredenin SB · 2008

[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · View source ↗

Kasian A, Kolomin T, Andreeva L, Bondarenko E, Myasoedov N, Slominsky P, Shadrina M · 2017

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats

Behavioural neurology · View source ↗

Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P · 2016

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission

Frontiers in pharmacology · View source ↗

Kolik LG, Nadorova AV, Antipova TA, Kruglov SV, Kudrin VS, Durnev AD · 2019

Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats

Bulletin of experimental biology and medicine · View source ↗

Medvedev VE, Tereshchenko ON, Israelian AIu, Chobanu IK, Kost NV, Sokolov OIu, Miasoedov NF · 2014

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders]

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · View source ↗

Zozulya AA, Kost NV, Yu Sokolov O, Gabaeva MV, Grivennikov IA, Andreeva LN, Zolotarev YA, Ivanov SV, Andryushchenko AV, Myasoedov NF, Smulevich AB · 2001

The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity

Bulletin of experimental biology and medicine · View source ↗

Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA, Aleksandrovna BO, Fedorovich MN, Aleksandrovna AL · 2021

The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress

Current reviews in clinical and experimental pharmacology · View source ↗

O. Y. Sokolov, V. K. Meshavkin, N. V. Kost, and A. A. Zozulya

Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions

Bull. Exp. Biol. Med. [PubMed] ·

O. N. Uchakina et al. · 2008

[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders]

Zh. Nevrol. Psikhiatr. Im. S. S. Korsakova ·

T. Kolomin, M. Shadrina, L. Andreeva, P. Slominsky, S. Limborska, and N. Myasoedov · 2011

Expression of inflammation-related genes in mouse spleen under tuftsin analog Selank

Regul. Pept ·

T. I. Agapova et al. · 2008

[Effect of semax on the temporary dynamics of brain-derived neurotrophic factor and nerve growth factor gene expression in the rat hippocampus and frontal cortex]

Mol. Genet. Mikrobiol. Virusol ·

T. P. Semenova, I. I. Kozlovskiĭ, N. M. Zakharova, and M. M. Kozlovskaia · 2010

[Experimental optimization of learning and memory processes by selank]

Eksp. Klin. Farmakol ·

T. A. Kolomin et al. · 2013

[c]

Zh. Vyssh. Nerv. Deiat. Im. I. P. Pavlova ·

T. P. Semenova, M. M. Kozlovskaya, N. M. Zakharova, I. I. Kozlovskii, and A. V. Zuikov

Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny

Bull. Exp. Biol. Med ·

N. V. Kost et al. · 2001

[Semax and selank inhibit the enkephalin-degrading enzymes from human serum]]

Bioorg. Khim ·

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