Melanotan-1, also known in literature as Melanotan I or afamelanotide, is a linear alpha-MSH analogue. It is usually discussed around MC1R-associated signalling, pigmentation pathway models, receptor selectivity, and peptide analogue stability.
The important comparison is structure. Melanotan-1 is a linear melanocortin analogue, while Melanotan II and PT-141 are cyclic analogues. That makes Melanotan-1 useful when the study focus is how sequence design changes melanocortin receptor behaviour.
This product is not positioned for cosmetic or body-use claims. It is a melanocortin-pathway research material, with identity, formula, mass, purity, and handling details covered by the specification table.
The references below are starting points for the mechanisms discussed here. The specification table on this page covers identity, formula, molecular mass, physical form, solubility, storage, and lot-level analytical information.
References
- PubChem search: Melanotan I afamelanotide
- PubMed: Melanotan I afamelanotide alpha-MSH
- PubMed: MC1R melanocortin peptide analogue
Research-use notice: Supplied strictly for lawful research, laboratory, analytical, educational, or R&D purposes where permitted by applicable law. Not for human or animal use, consumption, diagnosis, treatment, food, supplement, cosmetic, veterinary, or similar end use.




