
Peptide appearance
Lyophilized form helps protect peptide quality. Peptides are supplied as a dry powder, which may look like a compact "puck" or a lighter powder inside the vial.
Because the peptide is dry, it does not require refrigerated shipping during normal transit, including warm seasonal conditions. For longer storage, follow the storage guidance in the product description.
Appearance can vary. The stated peptide content is checked through third-party analysis.
Read more in the product description.
Solution not bundled
Peptides are delivered as lyophilized powder. This dry form helps preserve peptide quality during storage and transport and does not require refrigerated shipping during normal transit.
To prepare a solution, use a solvent such as Bacteriostatic water. It is sold separately, so add it only when you need it for peptide preparation.
Read more in the product description.
Mitochondrial peptide
MOTSC
In stock
MOTS-c is a peptide encoded in the mitochondrial 12S rRNA region. Published studies look at cellular energy, glucose, lipids, muscle, bone, and cardiovascular models.
Order within — · ships today Cutoff 10:00 · local time
Arrives Sep 21 - Sep 23 to Europe
MOTSC
Price range: 49,90 € through 148,50 €
Mitochondrial-derived peptide for cellular energy and stress-signalling studies.
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Research overview
MOTSC
MOTS-c is a short mitochondrial-derived peptide linked to MT-RNR1. Its mitochondrial origin makes it useful for studying cell communication and metabolic signals.
Studies cover exercise metabolism, insulin signals, mitochondrial stress, bone models, and cardiovascular observations. These reports provide research context, not a product result.
Mitochondrial and metabolic signalling
Studies measure AMPK-related signals, glucose use, lipid metabolism, and skeletal-muscle endpoints. Each result depends on the original laboratory system.
Other work looks at mitochondrial stress and changes in nuclear gene expression.
Muscle, bone, and cardiovascular models
Published work also covers exercise, bone, longevity, and cardiovascular models. These study types and their endpoints should be considered separately.
Compound information
Specifications
Molecular profile
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Molecular mass
- 2174.60 g/mol
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
Material record
- Physical appearance
- White to off-white lyophilized powder
- Solubility
- Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
- Product note
- Mitochondrial-derived 16-amino-acid peptide; supplied strictly for research use only.
Laboratory care
Handling
Peptides in transport
Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.
Storage of lyophilized peptides
Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:
- Room temperature (15–25 °C): Up to 3 months
- Refrigerated (2–8 °C): Up to 6 months
- Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)
Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.
Storage of reconstituted peptides
Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.
The following storage conditions are generally recommended:
- Room temperature (15–25 °C): Avoid prolonged storage
- Refrigerated (2–8 °C): Typically 4–8 weeks
- Frozen (-20 °C or below): Up to 3–4 months
To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.
Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.
Analytical documentation
Latest test results
Documentation is available on request
Contact us for the current record for this strength. We never substitute a generic or mismatched certificate.
Your batch is confirmed when your order is allocated.Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 10mg
99.2%Purity by HPLC
Recorded QC panel
- AssayPeptide screening
- 10.39 mg
- PurityPeptide screening
- 99.2%
- Identity (FTIR)FTIR spectrum
- 997
- Identity (RT)Retention time
- 0.989
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 40mg
99.7%Purity by HPLC
Recorded QC panel
- AssayPeptide screening
- 40.5 mg
- PurityPeptide screening
- 99.7%
- Identity (FTIR)FTIR spectrum
- 1000
- Identity (RT)Retention time
- 0.986
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
Source record
References
National Center for Biotechnology Information
PubChem Compound Summary: MOTS-c
Authoritative identity record for the mitochondrial-derived peptide MOTS-c.
PubChem · View source ↗Lee C, Zeng J, Drew BG, et al. · 2015
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Primary report identifying MOTS-c as a mitochondrial-derived peptide.
Cell Metabolism · 10.1016/j.cmet.2015.02.009 View source ↗Chemical Abstracts Service
CAS Common Chemistry: 1627580-64-6
Authoritative CAS Registry Number record for MOTS-c.
CAS Common Chemistry · View source ↗National Center for Biotechnology Information
NCBI Gene: MT-RNR1 mitochondrial 12S rRNA
Authoritative gene record for the mitochondrial transcript that encodes MOTS-c.
NCBI Gene · View source ↗Fuku N, Pareja-Galeano H, Zempo H, Alis R, Arai Y, Lucia A, Hirose N · 2015
The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?
Aging cell · View source ↗Kim SJ, Miller B, Mehta HH, Xiao J, Wan J, Arpawong TE, Yen K, Cohen P · 2019
The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity
Physiological reports · View source ↗Y. Zheng et al. · 2023
MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation
2023 ·C. Lee, K. H. Kim, and P. Cohen · 2016
MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism
Free Radic. Biol. Med ·H. Lu et al. · 2019
MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction
J. Mol. Med. Berl. Ger ·K. H. Kim, J. M. Son, B. A. Benayoun, and C. Lee · 2018
The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
Cell Metab ·R. Crescenzo, F. Bianco, A. Mazzoli, A. Giacco, G. Liverini, and S. Iossa · 2016
A possible link between hepatic mitochondrial dysfunction and diet-induced insulin resistance
Eur. J. Nutr ·L. R. Cataldo, R. Fernández-Verdejo, J. L. Santos, and J. E. Galgani · 2018
Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals
J. Investig. Med ·N. Che et al. · 2019
MOTS-c improves osteoporosis by promoting the synthesis of type I collagen in osteoblasts via TGF-β/SMAD signaling pathway
Eur. Rev. Med. Pharmacol. Sci ·B.-T. Hu and W.-Z. Chen · 2018
MOTS-c improves osteoporosis by promoting osteogenic differentiation of bone marrow mesenchymal stem cells via TGF-β/Smad pathway
Eur. Rev. Med. Pharmacol. Sci ·Q. Qin et al. · 2018
Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction
Int. J. Cardiol ·Y. Yang et al. · 2019



