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Peptide appearance Lyophilized form

Secretagogue peptide

Ipamorelin

In stock

Ipamorelin is a synthetic peptide made of five amino acids and used in ghrelin-receptor research. Published studies look at receptor selectivity, endocrine signals, bone and muscle models, and gut movement.

Available strengths
44,50 
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Ipamorelin

44,50 

Selective GHSR peptide for ghrelin receptor and endocrine marker studies.

SKU: ADRIA-IPAMORELIN Category:

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Research overview

Ipamorelin

Ipamorelin is an engineered five-amino-acid peptide, not a full-length natural hormone. Its sequence and terminal changes matter in receptor studies.

Studies cover ghrelin-receptor signals, endocrine responses, bone and muscle models, and gastrointestinal physiology. These observations apply only to the reported study conditions.

Ghrelin-receptor selectivity

Studies compare ghrelin-receptor ligands and measure growth-hormone-, ACTH-, and cortisol-related endpoints. The main question is how selective the ligand is in that assay.

Receptor-probe experiments help separate these signals from broader product claims.

Bone, muscle, and motility models

Other studies measure bone, muscle, metabolic, and postoperative gut-movement endpoints. Each result must stay linked to its own model and controls.

Compound information

Specifications

Molecular profile

Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular mass
711.9 g/mol
CAS number
170851-70-4
Molecular formula
C38H49N9O5

Material record

Physical appearance
White to off-white lyophilized powder
Solubility
Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
Product note
Selective growth hormone secretagogue peptide; supplied strictly for research use only.

Laboratory care

Handling

Peptides in transport

Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.

Storage of lyophilized peptides

Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Up to 3 months
  • Refrigerated (2–8 °C): Up to 6 months
  • Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)

Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.

Storage of reconstituted peptides

Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.

The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Avoid prolonged storage
  • Refrigerated (2–8 °C): Typically 4–8 weeks
  • Frozen (-20 °C or below): Up to 3–4 months

To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.

Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.

Analytical documentation

Latest test results

Latest published result

Liquilabs s.r.o.Signed Certificate of Analysis · 10mg

> 99.8%Purity by HPLC

Batch number
2025290
Tested
2026-05-28

Recorded QC panel

AssayPeptide screening
9.13 mg
PurityPeptide screening
> 99.8%
Identity (FTIR)FTIR spectrum
995
Identity (RT)Retention time
0.983

These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.

See all test results

Signed certificate

Source record

References

National Center for Biotechnology Information

PubChem Compound Summary: Ipamorelin

Authoritative identity record for Ipamorelin.

PubChem · View source ↗

Raun K, Hansen BS, Johansen NL, et al. · 1998

Ipamorelin, the first selective growth hormone secretagogue

Primary receptor-pharmacology study of Ipamorelin.

European Journal of Endocrinology · 10.1530/eje.0.1390552 View source ↗

Venkova K, Mann W, Nelson R, et al. · 2009

Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus

Primary study using Ipamorelin in a defined rodent research model.

Journal of Pharmacology and Experimental Therapeutics · 10.1124/jpet.108.149211 View source ↗

Chemical Abstracts Service

CAS Common Chemistry: 170851-70-4

Authoritative CAS Registry Number record for Ipamorelin.

CAS Common Chemistry · View source ↗

Gobburu JV, Agersø H, Jusko WJ, Ynddal L · 1999

Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers

Pharmaceutical research · View source ↗

Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H · 1999

Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · View source ↗

Beck DE, Sweeney WB, McCarter MD, Ipamorelin 201 Study Group · 2014

Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients

International journal of colorectal disease · View source ↗

Shrestha P, Sabharwal G, Ghaffari G · 2018

A Novel STAT3 Gene Mutation Related Hyper-IgE Syndrome Misdiagnosed as Hidradenitis Suppurativa

Case reports in immunology · View source ↗

N. B. Andersen, K. Malmlöf, P. B. Johansen, T. T. Andreassen, G. Ørtoft, and H. Oxlund · 2001

The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats

Growth Horm. IGF Res. Off. J. Growth Horm. Res. Soc. Int. IGF Res. Soc ·

J. Svensson et al. · 2000

The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats

J. Endocrinol ·

N. K. Aagaard et al. · 2009

Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats

Growth Horm. IGF Res. Off. J. Growth Horm. Res. Soc. Int. IGF Res. Soc ·

E. Adeghate and A. S. Ponery · 2004

Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats

Neuro Endocrinol. Lett ·

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