IGF-1 LR3, also called Long R3 IGF-1, is a modified IGF-1 analogue. It is usually discussed with an N-terminal extension and an arginine substitution that changes how the molecule is compared with native IGF-1 in receptor and binding-protein models.
The key research interest is signalling through the IGF-1 receptor and related pathways such as PI3K/AKT and MAPK in controlled cell-model systems. It is also relevant when customers need to compare IGF-1 analogues, binding-protein interaction, and larger protein-style research materials.
Because IGF-1 LR3 is larger and more protein-like than many short peptides, identity, handling, and storage details matter. The specification table gives the supplied sequence, molecular profile, purity, and lot-level analytical information.
The references below are starting points for the mechanisms discussed here. The specification table on this page covers identity, formula, molecular mass, physical form, solubility, storage, and lot-level analytical information.
References
- PubChem search: Long R3 IGF-1
- PubMed: Long R3 IGF-1
- PubMed: IGF-1 receptor signalling
- UniProt: human IGF1 reference
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