Peptide appearance
Lyophilized form helps protect peptide quality. Peptides are supplied as a dry powder, which may look like a compact "puck" or a lighter powder inside the vial.
Because the peptide is dry, it does not require refrigerated shipping during normal transit, including warm seasonal conditions. For longer storage, follow the storage guidance in the product description.
Appearance can vary. The stated peptide content is checked through third-party analysis.
Read more in the product description.
Solution not bundled
Peptides are delivered as lyophilized powder. This dry form helps preserve peptide quality during storage and transport and does not require refrigerated shipping during normal transit.
To prepare a solution, use a solvent such as Bacteriostatic water. It is sold separately, so add it only when you need it for peptide preparation.
Read more in the product description.
Copper peptide
GHK-CU
In stock
GHK-Cu is the copper complex of the peptide glycyl-L-histidyl-L-lysine. Published studies look at copper binding, extracellular matrix, microbes, nerve cells, and gene expression.
Order within — · ships Wed, 23 Sep Cutoff 10:00 · local time
Arrives Sep 28 - Sep 30 to Europe
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GHK-CU
Price range: 38,50 € through 62,00 €
GHK-Cu copper peptide complex for matrix, copper-signalling, and remodeling studies.
Research overview
GHK-CU
GHK-Cu combines a defined three-amino-acid peptide with copper. Its complex form, copper binding, and analytical identity matter when studies are compared.
Studies cover matrix-related cell work, microbial tests, nervous-system models, and gene activity. They provide research context, not a promised result for this material.
Copper binding and matrix models
Studies measure copper binding, fibroblast activity, collagen markers, and extracellular-matrix signals. These topics support controlled chemistry and cell-culture work.
Gene-expression studies must be read with their exact tissue, timepoint, and test method.
Microbial and neural research
Other studies use microbial tests and nervous-system models. These model types should be read separately instead of combined into one broad claim.
Compound information
Specifications
Molecular profile
- Sequence
- Gly-His-Lys
- Molecular mass
- 401.91 g/mol
- CAS number
- 89030-95-5
- Molecular formula
- C14H22CuN6O4
Material record
- Physical appearance
- Blue to blue-green lyophilized powder
- Salt form
- 1:1 GHK–Cu(II) complex
- Solubility
- Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
- Product note
- Copper-binding tripeptide complex; supplied strictly for research use only.
Laboratory care
Handling
Peptides in transport
Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.
Storage of lyophilized peptides
Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:
- Room temperature (15–25 °C): Up to 3 months
- Refrigerated (2–8 °C): Up to 6 months
- Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)
Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.
Storage of reconstituted peptides
Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.
The following storage conditions are generally recommended:
- Room temperature (15–25 °C): Avoid prolonged storage
- Refrigerated (2–8 °C): Typically 4–8 weeks
- Frozen (-20 °C or below): Up to 3–4 months
To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.
Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.
Analytical documentation
Tests
Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 50mg
> 99.8%Purity by HPLC
Recorded QC panel
- AssayPeptide screening
- 44.4 mg
- PurityPeptide screening
- > 99.8%
- Identity (FTIR)FTIR spectrum
- 987
- Identity (RT)Retention time
- 1.000
- Bacterial EndotoxinUSP / Eur. Ph. 2.6.14
- 0.004 EU/mg
- Molecular Ion MassMS deconvolution
- 341 Da
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 100mg
> 99.8%Purity by HPLC
Recorded QC panel
- AssayPeptide screening
- 89.4 mg
- PurityPeptide screening
- > 99.8%
- Identity (FTIR)FTIR spectrum
- 987
- Identity (RT)Retention time
- 0.991
- Bacterial EndotoxinUSP / Eur. Ph. 2.6.14
- 0.002 EU/mg
- Molecular Ion MassMS deconvolution
- 341 g/mol
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
Source record
References
Badenhorst T, Svirskis D, Merrilees MJ, et al. · 2016
Physicochemical characterization of native glycyl-l-histidyl-l-lysine tripeptide for wound healing and anti-aging: a preformulation study for dermal delivery
Physicochemical and stability characterisation of GHK-Cu.
Pharmaceutical Development and Technology · 10.3109/10837450.2014.979944 View source ↗National Center for Biotechnology Information
PubChem Compound Summary: GHK-Cu
Authoritative identity record for the GHK-Cu copper-peptide complex.
PubChem · View source ↗Chemical Abstracts Service
CAS Common Chemistry: 49557-75-7
Authoritative CAS Registry Number record for GHK-Cu.
CAS Common Chemistry · View source ↗National Center for Biotechnology Information
PubChem compound record
PubChem · View source ↗Pickart L, Margolina A · 2018
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
International journal of molecular sciences · View source ↗Pickart L, Vasquez-Soltero JM, Margolina A · 2015
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
BioMed research international · View source ↗A. Gruchlik, E. Chodurek, and Z. Dzierzewicz · 2014
Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts
Acta Pol. Pharm ·X. Wang et al. · 2017
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis
Wound Repair Regen. Off. Publ. Wound Heal. Soc. Eur. Tissue Repair Soc ·M. Kukowska, M. Kukowska-Kaszuba, and K. Dzierzbicka · 2015
In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections
Bioorg. Med. Chem. Lett ·G. D. Mulder et al. · 1994
Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper
Wound Repair Regen. Off. Publ. Wound Heal. Soc. Eur. Tissue Repair Soc ·S. O. Canapp et al. · 2003
The effect of topical tripeptide-copper complex on healing of ischemic open wounds
Vet. Surg. VS ·L. Pickart, J. M. Vasquez-Soltero, and A. Margolina · 2017
The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline
Brain Sci ·H. Zhang, Y. Wang, and Z. He · 2018
Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway
Front. Neurosci ·X.-M. Zhou et al. · 2017
GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
Front. Pharmacol ·J.-R. Park, H. Lee, S.-I. Kim, and S.-R. Yang · 2016
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Oncotarget ·L. А. Sever'yanova and M. E. Dolgintsev · 2017
Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats
Bull. Exp. Biol. Med ·L. А. Sever'yanova and D. V. Plotnikov · 2018
Binding of Glyprolines to L-Arginine Inverts Its Analgesic and Antiagressogenic Effects
Bull. Exp. Biol. Med ·Customer reviews
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