Buy 2, save 5%Buy 3+, save 9%Buy 6+, save 15%Buy 10+, save 22%Free EU & Balkan shipping over €1503rd-party tested batchesTest results available through the libraryCzech Republic fulfillmentResearch use onlyBuy 2, save 5%Buy 3+, save 9%Buy 6+, save 15%Buy 10+, save 22%Free EU & Balkan shipping over €1503rd-party tested batchesTest results available through the libraryCzech Republic fulfillmentResearch use only
Lyophilized form helps protect peptide quality. Peptides are supplied as a dry powder, which may look like a compact "puck" or a lighter powder inside the vial.
Because the peptide is dry, it does not require refrigerated shipping during normal transit, including warm seasonal conditions. For longer storage, follow the storage guidance in the product description.
Appearance can vary. The stated peptide content is checked through third-party analysis.
Read more in the product description.
Solution not bundled
Peptides are delivered as lyophilized powder. This dry form helps preserve peptide quality during storage and transport and does not require refrigerated shipping during normal transit.
To prepare a solution, use a solvent such as Bacteriostatic water. It is sold separately, so add it only when you need it for peptide preparation.
Read more in the product description.
Peptide research
Epitalon
In stock
Epithalon is a synthetic peptide made of four amino acids. Published studies look at telomerase, DNA-repair markers, melatonin, and cell cultures.
MassQuantity
38,00 €38,00 €
Order within — · ships today
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Arrives Sep 21 - Sep 23
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Epitalon · 1 vial138,00 €38,00 €
Epitalon
38,00 €–124,90 €Price range: 38,00 € through 124,90 €
Epitalon tetrapeptide for pineal, circadian, and telomere-pathway studies.
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Research overview
Epitalon
Epithalon, also written Epitalon, has the sequence Ala-Glu-Asp-Gly. Its short, defined sequence supports controlled identity and sequence-based work.
Studies measure telomerase activity, DNA markers, pineal signals, and cell-culture changes. Each finding stays tied to the model used in the paper.
Cell-ageing markers
Studies measure telomerase activity, telomere length, DNA-repair markers, and cell division. These are research measurements, not a statement about product performance.
Other work looks at oxidative stress and fibroblast models. The original protocol and comparison group are needed to understand the results.
Pineal and melatonin research
Separate studies look at pineal-cell cultures and melatonin-related measurements. They provide context for research on endocrine and cell signalling.
Compound information
Specifications
Molecular profile
Sequence
Ala-Glu-Asp-Gly
Molecular mass
390.35 g/mol
CAS number
307297-39-8
Molecular formula
C14H22N4O9
Material record
Physical appearance
White to off-white lyophilized powder
Solubility
Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
Product note
Synthetic pineal tetrapeptide analogue; discussed in cellular ageing, circadian, oxidative-stress, and telomere-associated controlled research; supplied strictly for research use only.
Laboratory care
Handling
Peptides in transport
Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.
Storage of lyophilized peptides
Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:
Room temperature (15–25 °C): Up to 3 months
Refrigerated (2–8 °C): Up to 6 months
Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)
Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.
Storage of reconstituted peptides
Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.
The following storage conditions are generally recommended:
Room temperature (15–25 °C): Avoid prolonged storage
Refrigerated (2–8 °C): Typically 4–8 weeks
Frozen (-20 °C or below): Up to 3–4 months
To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.
Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.
Analytical documentation
Latest test results
Latest published result
Liquilabs s.r.o.Signed Certificate of Analysis · 10mg
98.1%Purity by HPLC
Batch number
2321092
Tested
2026-07-27
Recorded QC panel
AssayPeptide screening
8.96 mg
PurityPeptide screening
98.1%
Identity (FTIR)FTIR spectrum
982
Identity (RT)Retention time
1.000
Bacterial EndotoxinUSP / Eur. Ph. 2.6.14
0.040 EU/mg
Molecular Ion MassMS deconvolution
390 g/mol
These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.
On request
Documentation is available on request
Contact us for the current record for this strength. We never substitute a generic or mismatched certificate.
Your batch is confirmed when your order is allocated.
Peptide promotes overcoming of the division limit in human somatic cell
Bulletin of experimental biology and medicine ·
View source ↗
V. Kh. Khavinson, A. A. Pendina, O. A. Efimova, A. V. Tikhonov, A. S. Koltsova, M. I. Krapivin, A. V. Petrovskaia-Kaminskaia, L. I. Petrova, N. S. Lin’kova, V. S. Baranov · 2019
Effect of Peptide AEDG on Telomere Length and Mitotic Index of PHA-Stimulated Human Blood Lymphocytes
Bulletin of Experimental Biology and Medicine · 10.1007/s10517-019-04664-0
View source ↗
Khavinson V, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B · 2020
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
Vladimir N. Anisimov, Vladimir Kh. Khavinson, Anatoli I. Mikhalski, Anatoli I. Yashin · 2001
Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice
Mechanisms of Ageing and Development · 10.1016/s0047-6374(00)00184-6
View source ↗
N. D. Goncharova, B. Kh. Khavinson, B. A. Lapin · 2001
Regulatory Effect of Epithalon on Production of Melatonin and Cortisol in Old Monkeys
Bulletin of Experimental Biology and Medicine · 10.1023/a:1017928925177
View source ↗
Vladimir N. Anisimov, Vladimir KH. Khavinson, Mauro Provinciali, Irina N. Alimova, Dmitri A. Baturin, Irina G. Popovich, Mark A. Zabezhinski, Eugeni N. Imyanitov, Romina Mancini, Claudio Franceschi · 2002
Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice
International Journal of Cancer · 10.1002/ijc.10570
View source ↗
V. Kh. Khavinson, N. S. Linkova, I. M. Kvetnoy, T. V. Kvetnaia, V. O. Polyakova, H.-W. Korf · 2012
Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture
Bulletin of Experimental Biology and Medicine · 10.1007/s10517-012-1689-5
View source ↗
E. O. Gutop, N. S. Linkova, E. O. Kozhevnikova, N. V. Fridman, O. M. Ivko, V. Kh. Khavinson · 2022
AEDG Peptide Prevents Oxidative Stress in the Model of Induced Aging of Skin Fibroblasts
Advances in Gerontology · 10.1134/s2079057022020096
View source ↗
V. N. Anisimov, S. V. Mylnikov, and V. K. Khavinson · 1998
Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats
Mech. Ageing Dev ·
T. A. Dzhokhadze, T. Z. Buadze, M. N. Gaiozishvili, M. A. Rogava, and T. A. Lazhava · 2013
[Functional regulation of genome with peptide bioregulators by hypertrophic cardiomyopathy (by patients and relatives)]
Georgian Med. News ·
V. N. Anisimov et al. · 2003
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Biogerontology ·
V. K. Khavinson, S. I. Tarnovskaya, N. S. Linkova, V. E. Pronyaeva, L. K. Shataeva, and P. P. Yakutseni · 2013
Short cell-penetrating peptides: a model of interactions with gene promoter sites
Bull. Exp. Biol. Med ·
N. S. Lin'kova, B. I. Kuznik, and V. K. Khavinson · 2012
[Peptide Ala-Glu-Asp-Gly and interferon gamma: their role in immune response during aging]
Adv. Gerontol. Uspekhi Gerontol ·
N. I. Chalisova, N. S. Lin'kova, A. N. Zhekalov, A. O. Orlova, G. A. Ryzhak, and V. K. Khavinson · 2014
[Short peptides stimulate skin cell regeneration during ageing]
Adv. Gerontol. Uspekhi Gerontol ·
N. S. Lin'kova et al. · 2016
Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro
Bull. Exp. Biol. Med ·
I. A. Vinogradova, A. V. Bukalev, M. A. Zabezhinski, A. V. Semenchenko, V. K. Khavinson, and V. N. Anisimov · 2007
Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes
Bull. Exp. Biol. Med ·
G. Kossoy, V. N. Anisimov, H. Ben-Hur, N. Kossoy, and I. Zusman · 2006
Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice
Vivo Athens Greece ·
V. N. Anisimov et al. · 2002
Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
Int. J. Cancer ·
V. N. Anisimov, V. K. Khavinson, I. N. Alimova, A. V. Semchenko, and A. I. Yashin · 2002
Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice
Bull. Exp. Biol. Med ·
I. A. Vinogradova, A. V. Bukalev, M. A. Zabezhinski, A. V. Semenchenko, V. K. Khavinson, and V. N. Anisimov · 2008
Geroprotective effect of ala-glu-asp-gly peptide in male rats exposed to different illumination regimens
Bull. Exp. Biol. Med ·
S. Gery, N. Komatsu, L. Baldjyan, A. Yu, D. Koo, and H. P. Koeffler · 2006
The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells
Mol. Cell ·
V. K. Khavinson, L. K. Shataeva, and A. A. Chernova · 2003
Effect of regulatory peptides on gene transcription
Bull. Exp. Biol. Med ·
O. V. Korkushko et al. · 2007
[Normalizing effect of the pineal gland peptides on the daily melatonin rhythm in old monkeys and elderly people]
Adv. Gerontol. Uspekhi Gerontol ·
V. Khavinson, M. Razumovsky, S. Trofimova, R. Grigorian, and A. Razumovskaya · 2002
Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa
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