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Peptide appearance Lyophilized form

GHRH analogue

CJC-1295 with DAC

In stock

CJC-1295 with DAC is a synthetic GHRH analogue with a drug-affinity-complex modification. Published studies look at albumin binding, longer circulation, and endocrine signals.

Available strengths
88,90 
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CJC-1295 with DAC

88,90 

DAC-linked GHRH analogue for albumin-binding and extended-exposure pathway studies.

SKU: ADRIA-CJC-DAC Category: Tags: ,

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Research overview

CJC-1295 with DAC

The DAC modification makes this analogue different from modified GRF(1-29) without DAC. This difference matters when comparing binding, duration, and receptor-signalling studies.

Studies measure growth-hormone release, growth-related markers, and reproductive-system signals. These are study findings, not claims about the supplied material.

Albumin binding and signalling duration

The DAC group is designed to bind albumin and extend circulation in laboratory models. Researchers compare how this changes exposure and endocrine measurements versus a no-DAC analogue.

Each comparison should use the exact sequence, assay, and observation time reported in the paper.

Endocrine model endpoints

Published studies also measure growth-hormone and IGF-related endpoints. These measurements do not define the quality or behaviour of a supplied lot.

Compound information

Specifications

Molecular profile

Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(N-epsilon-maleimidopropionyl)-NH2
Molecular mass
3647.2 g/mol
CAS number
446262-90-4
Molecular formula
C165H269N47O46

Material record

Physical appearance
White to off-white lyophilized powder
Solubility
Soluble in bacteriostatic water and suitable aqueous laboratory solvents.
Product note
Albumin-binding GHRH analogue research compound; supplied strictly for research use only.

Laboratory care

Handling

Peptides in transport

Peptides in lyophilized form are supplied in glass vials by standard shipping methods and do not require refrigeration. Short-term temperature fluctuations during transport will not reduce their quality and efficacy. Even at high summer temperatures, the peptides in lyophilized form are stable for several weeks.

Storage of lyophilized peptides

Lyophilized peptides should be stored in a dry place, protected from light and moisture. The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Up to 3 months
  • Refrigerated (2–8 °C): Up to 6 months
  • Frozen (-20 °C or below): 3–5 years (recommended for long-term storage)

Allow the vial to reach room temperature after taking it out of the refrigerator or freezer.

Storage of reconstituted peptides

Once reconstituted, peptide solutions are generally less stable than their lyophilized form and should be stored under refrigerated conditions whenever possible.

The following storage conditions are generally recommended:

  • Room temperature (15–25 °C): Avoid prolonged storage
  • Refrigerated (2–8 °C): Typically 4–8 weeks
  • Frozen (-20 °C or below): Up to 3–4 months

To preserve peptide integrity, avoid repeated freeze–thaw cycles, as these may accelerate peptide degradation.

Important: Most manufacturers recommend discarding reconstituted peptides within 4 weeks when stored at 2–8 °C. This recommendation is intentionally conservative and may not reflect the actual chemical stability of every peptide. In our own stability studies, many peptides reconstituted in bacteriostatic water showed no detectable degradation after 12 weeks of refrigerated storage. As peptide stability is highly sequence- and formulation-dependent, this result should not be extrapolated to all peptides without supporting stability data.

Analytical documentation

Latest test results

Latest published result

Liquilabs s.r.o.Signed Certificate of Analysis · 5 mg

Certificate preview for 5 mg

98.6%Purity by HPLC

Batch number
6158307
Tested
2026-09-08

Recorded QC panel

AssayPeptide Screening 0.1% TFA
4.10 mg (± 0.02 mg)
PurityPeptide Screening 0.1% TFA
98.6%
Identity (FTIR)Peptide Screening 0.1% TFA
980 (± 5)
Identity (RT)Retention time
0.997 (± 0.005)
Bacterial endotoxinUSP 85 / Eur. Ph. 2.6.14
Less than 0.001 EU/mg

These are the latest published results for this strength. The batch number is printed on each vial. Your supplied batch is confirmed against the matching published record when your order is allocated.

See all test results

Signed certificate

Source record

References

National Center for Biotechnology Information

PubChem Compound Summary: CJC-1295

Authoritative identity record for CJC-1295 with DAC.

PubChem · View source ↗

Teichman SL, Neale A, Lawrence B, et al. · 2006

Prolonged stimulation of growth hormone and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of growth hormone-releasing hormone, in healthy adults

Primary characterisation of CJC-1295 as a long-acting GHRH analogue.

Journal of Clinical Endocrinology and Metabolism · 10.1210/jc.2005-1536 View source ↗

Sackmann-Sala L, Ding J, Frohman LA, et al. · 2009

Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects

Primary CJC-1295 study reporting serum-protein profiling.

Growth Hormone and IGF Research · 10.1016/j.ghir.2009.03.001 View source ↗

M. Ionescu and L. A. Frohman · 2006

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

J. Clin. Endocrinol. Metab ·

· 2005

Sam L. Teichman et al., „Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults, 91(3):799-805, Epub 2005 Dec 13

·

M. Alba et al. · 2006

Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse

Am. J. Physiol. Endocrinol. Metab ·

A. Volpe, G. Coukos, A. Barreca, G. Giordano, P. G. Artini, and A. R. Genazzani · 1991

Clinical use of growth hormone-releasing factor for induction of superovulation

Hum. Reprod ·

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